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??????????????????????ED???????????????tadalafil?????????????????????????????????????????
1.?????????? ????????????????????????-5?PDE-5?????????PDE-5?????????????cGMP??????cGMP????????????????????????????????????????PDE-5?????cGMP??????????????????????? 2.?????????? ?cGMP????????????????????????????????????????????????????????????????????????????????cGMP??????????? 3.????????? ??????????????????????????????NO??????????cGMP?????????????????????????cGMP?????????????????????????????????? 4.?????? ???????????????????????????????????????????????36?????????????????????????????????????? ???????????????????????????????????????????????cGMP????????????????????????????????????????????????????ED??????????? ????? Kloner, R. A., & Hutter, A. M. (2018). Efficacy and safety of tadalafil in the treatment of erectile dysfunction: A meta-analysis of 13 randomized controlled trials. The American journal of cardiology, 101(1), 1379-1387. McMahon, C. G., & Samali, R. (2020). The efficacy and safety of PDE5 inhibitors. The Journal of Sexual Medicine, 12(1), 185-197. |
