??????????????Dapoxetine???????????????????????????????????????????????????????????????
???????????????? ????????????????? 1.??????? ?????????????????????????????CYP3A4???????????????????????????????? 2.???????? ????????????????????????CYP3A4?????????????????????????????????????????????? ???????????? 1.????????? ????????????????????????????????????????????????????????????????????? 2.??????? ???????????????????????????????????????????????????????????????????????????????????
1.?????? ??????????????????????????????????????????????????????????? 2.???????? ??????????????????????????????????????????????? 3.????? ??????????????????????????????????????? ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????? ????? 1.Modi, N. B., Dresser, M. J., Simon, M., & Lin, D. (2013). Interaction between the selective serotonin reuptake inhibitor dapoxetine and alcohol in healthy male subjects. Journal of Clinical Pharmacology, 53(9), 955-961. 2.United States Food and Drug Administration. (2012). Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers. |