?????????????????????????????????????????????????????????????????????????????????????????????????????????????????? 1. ?????????????? a. ???????? ????????????????????????????????????????????????????????????????????????????????????? b. ??????????? ????????????????????????????????????? 2. ?????????????????? a. ????? ???????????????????????????? b. ??????? ??????????????????????? c. ??????? ?????????????????????????????????? 3. ????????????????? a. ????? ?????????Tadalafil??????????-5?PDE5???????????????????????????????? b. ????? ??????????????????????36????????????????? ???????????????????????????????????????????????????????????????4???????????? ????: 1.Andersson, K. E. (2011). PDE5 inhibitorspharmacology and clinical applications 20 years after sildenafil discovery. British journal of pharmacology, 164(1), 114. 2.Kloner, R. A., & Goldstein, I. (2000). Erectile dysfunction and the cardiovascular patient: endothelial dysfunction is the common denominator. Heart, 84(3), 226232. |