?????????

1.1????????,?IgA????????????;???????? ?????????????????;

1.2????????????,?????????????????????;

1.3???????,??????????????????????;

1.4??????,?????Alport????;

1.5??????,????????????;

1.6????????,??????????????????????;

1.7??????,?????????????????;

1.8??????,??????;?????????????

2???????????

2.1???:?????????????,???????????????

2.2???:???????????????????d3??,??????

2.3????:??????????????????,????????????????????????

2.4???�??�?:????????????????,??????????????????????????

2.5????:????????????,??????????

2.6???:????????????????????????????????????

2.7???????:??????????????????,??????????,???????????????????

3???????????

???:????????,?????,???????????

???:????????????,???????????????,????????????

????:GFR50?80ml/min,?????????,?????????;GFR50?20ml/min,???186?442?mol/L,?????7.1mmol/L,??????????;GFR20?10ml/min,???451?707?mol/L,???17.9?28.6mmol/L???????; GFR??10ml/min,?????707?mol/L,???28.6mmol/L??,????????????????,??????????????????

1???????????????????????????,???????????,???????,??????,????????,??????????????????????,????????

2?????????????:

?????????????????????????????????????????,?????????,??????????????,??????????????

??????????????????????????????,???????

3???????????????????????????,??????15????10?????30????15?????30?????20?,??200??,????1??

1?????????:?????????????,????????????????????????

2??????:??????????????????

3??????:??????,??????????????????????,??????????????,????????????

4????:?????????????????????????????????,???????,?????????????????,??????,??????40????????,??????????,??,???,????,????????

5??????:?????????????????????????????????????,????????????????????????,??????????????????,???????????